Week six delivered a chaotic fantasy landscape with a rash of injuries and a handful of breakout performances. Brian Thomas Jr. delivered a true breakout, Kamani Vidal seized a lead back role with a strong showing, and Derrick Henry finally supplied a usable line after a drought. Puka Nakua and DK Metcalf weathered injury chatter with returns that mattered for shiny matchups, while the waivers loom with potential every week.

Key takeaways: chase backfield opportunities where a lead can flip, decide if Brian Thomas Jr. is a hold or a sell high after a red-hot game, monitor rest-of-season schedules for rookies, and weigh the odds on veterans like Henry and Metcalf amid shifting spreads and injury notes as we move toward the fantasy playoffs.